Technologies
Mass Spectrometry for the Life Sciences
Discover novel biomarkers and therapeutic targets with PBL’s integrated mass spectrometry-based proteomic solutions. Our unique automated workflows and robust bioinformatics platform allow for the complete proteome search and quick translation from protein discovery to clinically validated targeted panels. Our high-throughput facility and unbiased technology enables the analysis of thousands of samples with depth, high reproducibility, and precision.
Our Proteomics Workflow
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Transforming Samples Into Quality Reliable Insightful Answers.
Accelerating Precision Proteomics:
From Discovery to Clinical Application
Proteomics plays a critical role in precision medicine by providing detailed information about the proteins present in all cells and tissues, which can be used to understand the molecular mechanisms of disease, personalize treatment plans, and monitor treatment efficacy. PBL’s proteomic services are driven by two platforms: ProteoSweep™ for Discovery and ProteoMarker™ for Targeted, that synergistically work to answer complex proteomics question and advance precision medicine through:
- Identifying new biomarkers for disease: Discovering new proteins or protein modifications that are associated with specific diseases, which can be used to develop new diagnostic tests and therapies.
- Understanding the molecular mechanisms of disease: Monitoring the changes in protein expression and function that occur in different diseases, providing insights into the underlying biological processes that contribute to disease development and progression.
- Personalizing treatment plans: Identifying specific proteins or protein changes that are associated with a patient's response to a particular treatment, allowing for the development of personalized treatment plans that are tailored to an individual's unique needs.
- Monitoring treatment efficacy: Monitoring the changes in protein expression and function that occur in response to treatment, providing information about the effectiveness of a particular treatment and allowing for adjustments to be made as needed.
Expert Services
Discovery Proteomics - ProteoSweep™
Targeted Proteomics - ProteoMarker™
Advanced Capabilities
PBL offers additional services and technologies designed to meet all customer needs or project requirements.
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Microsampling with Neoteryx by Trajan
Remote sample collection service integrated with our proteomics platforms, ensuring precise, minimal volumes for stress-free protein analysis and optimal results.
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Nanoparticles with the Proteograph Suite from SEER
Fully automated nanoparticle-based platform, providing deep unbiased proteome coverage, coupled with a rapid and scalable workflow that ensures efficient project completion with minimal hands-on time.