Technologies

Targeted Proteomics

PBL’s high-throughput targeted mass spectrometry platform, ProteoMarker™, allows for absolute quantification of pre-selected biomarkers with high specificity, selectivity, and accuracy. ProteoMarker™ offers rapid simultaneous measurements of multiple proteins at once (multiplexing), allowing complete independence from antibody-based recognition and availability. Targeted proteomics coupled with our immunoassays can efficiently quantify low-abundant proteins. PBL offers off-the-shelf panels or our experts will help you design and develop new custom assays.

Applications + PBL Expertise

MRM Targeted Proteomics Design

1 - PROTEIN SELECTION

Candidate proteins are selected, based on:
  • Project Goals
  • Scientific Literature
  • DDA/DIA or other discovery data

2 - PEPTIDE SELECTION

How to choose the right peptides:
  • Best Flying - Sensitivity
  • Unique - Selectivity

Resources include online repositories, in-house data, and predictive algorithms.

3 - TRANSITIONS SELECTION

How to choose the right transitions:
  • Most Abundant - Sensitivity
  • Unique - Selectivity

Resources include online repositories and in-house data.

Integrated Workflow + Targeted Components

Jump ahead with us!

Discuss and plan your next project with our talented team of proteomics experts!